ALEX Resources

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Lesson Plans (1) A detailed description of the instruction for teaching one or more concepts or skills. Learning Activities (1) Building blocks of a lesson plan that include before, during, and after strategies to actively engage students in learning a concept or skill. Classroom Resources (1)


ALEX Lesson Plans  
   View Standards     Standard(s): [SC2015] BIOL (9-12) 3 :
3 ) Formulate an evidence-based explanation regarding how the composition of deoxyribonucleic acid (DNA) determines the structural organization of proteins.

a. Obtain and evaluate experiments of major scientists and communicate their contributions to the development of the structure of DNA and to the development of the central dogma of molecular biology.

b. Obtain, evaluate, and communicate information that explains how advancements in genetic technology (e.g., Human Genome Project, Encyclopedia of DNA Elements [ENCODE] project, 1000 Genomes Project) have contributed to the understanding as to how a genetic change at the DNA level may affect proteins and, in turn, influence the appearance of traits.

c. Obtain information to identify errors that occur during DNA replication (e.g., deletion, insertion, translocation, substitution, inversion, frame-shift, point mutations).

Subject: Science (9 - 12)
Title: DNA Mutations
Description:

This is a technology based, hands-on Biology lesson on the types of mutations that can occur during DNA replication. Students will complete a virtual lab on DNA Mutations. Mutations involve a physical change to genetic material that results in the abnormal encoding of protein sequences. The students will complete mRNA and protein sequences based on the information provided. The students will identify the number of amino acids changed and how they think this mutation will impact the organism.

This lesson plan results from a collaboration between the Alabama State Department of Education and ASTA.




ALEX Learning Activities  
   View Standards     Standard(s): [SC2015] BIOL (9-12) 3 :
3 ) Formulate an evidence-based explanation regarding how the composition of deoxyribonucleic acid (DNA) determines the structural organization of proteins.

a. Obtain and evaluate experiments of major scientists and communicate their contributions to the development of the structure of DNA and to the development of the central dogma of molecular biology.

b. Obtain, evaluate, and communicate information that explains how advancements in genetic technology (e.g., Human Genome Project, Encyclopedia of DNA Elements [ENCODE] project, 1000 Genomes Project) have contributed to the understanding as to how a genetic change at the DNA level may affect proteins and, in turn, influence the appearance of traits.

c. Obtain information to identify errors that occur during DNA replication (e.g., deletion, insertion, translocation, substitution, inversion, frame-shift, point mutations).

Subject: Science (9 - 12)
Title: The Secret Code of Life
Description:

This interactive website allows students to examine the process of how each protein is coded for in the deoxyribonucleic acid (DNA) which hold the “The Secret Code of Life”. Students are able to manipulate models to explore transcription to demonstrate how complementary nucleotides bind to ensure a correct copy. Next, students are able to manipulate and observe, step by step, the process of translation. Students are then able to observe the folding of proteins and experiment with a protein model simulation. Lastly, students are able to apply mutations to a simulated protein sequence to observe what happens to the protein.

This activity was created as a result of the GAP Resource Summit.




ALEX Learning Activities: 1

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ALEX Classroom Resources  
   View Standards     Standard(s): [SC2015] BIOL (9-12) 3 :
3 ) Formulate an evidence-based explanation regarding how the composition of deoxyribonucleic acid (DNA) determines the structural organization of proteins.

a. Obtain and evaluate experiments of major scientists and communicate their contributions to the development of the structure of DNA and to the development of the central dogma of molecular biology.

b. Obtain, evaluate, and communicate information that explains how advancements in genetic technology (e.g., Human Genome Project, Encyclopedia of DNA Elements [ENCODE] project, 1000 Genomes Project) have contributed to the understanding as to how a genetic change at the DNA level may affect proteins and, in turn, influence the appearance of traits.

c. Obtain information to identify errors that occur during DNA replication (e.g., deletion, insertion, translocation, substitution, inversion, frame-shift, point mutations).

Subject: Science (9 - 12)
Title: Life's Instruction Manual: Interactive Lesson | UNC-TV Science
URL: https://aptv.pbslearningmedia.org/resource/ilunctv18-sci-ilmanual/lifes-instruction-manual-interactive-unc-tv-science/
Description:

The human genome serves as an instruction manual for life, with its own distinct letters, alphabet, sentences, and chapters. Learn about the genome, nucleotides, DNA, and genes with this interactive lesson.



ALEX Classroom Resources: 1

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